[TucsonDon]

My biggest concern would be tires.

I agree. I'm no mechanic, but it seems to me the fundamental components of the bike -- engine, drive train, fuel system -- will likely do fine. Weird things can happen, but the chances are relatively small. But the tires are a weak link. Heck, they're a weak link for all of us -- we can't carry a spare, or not easily anyway. So the advice to replace the tires prior to the trip if they show wear is good. Take a tire repair kit. And be very aware of where you're taking the thing. I've not driven the roads up there, but I understand some of the roads are hell on tires ... something about volcanic rock or something.