I'm going to amend this a little, if you have a lot of miles there have been 'discussions' that changing to a synthetic can have some negative long term affects - not sure I believe it, but the syn is capable of cleaning up a lot of deposits (some of which could be beneficial )
Some anectdotal evidence has been offered in the past about changing to syn in a car with 100k miles and then it had problems shortly thereafter.....I suspect it was due for problems either way....but just consider it as a potential for not changing to Synthetic.
I changed to syn at 26k miles and everything was fine, I am back now to dino-piss using the Rotella HD 15-40, as I think that works almost as well especially for the money.